2001 DEC 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The choice of conditioning regimens for stem cell transplantation may determine the rate of donor cell chimerism, researchers in Japan say.
Dr. Yoichi Takaue and colleagues at the National Cancer Center Hospital in Tokyo evaluated the effects of a reduced-intensity fludarabine-busulfan regimen on lineage-specific chimerism.
Patients treated with this regimen displayed myeloid and T-cell chimerism rates distinctly different from those seen in patients who underwent other conditioning regimens, they found.
Eight hematological cancer patients who were ineligible for …

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